Seraseq® ctDNA Reference Material v2 AF0.125%

To overcome the lack of patient-like reference materials for liquid biopsy, including drawbacks of existing methodologies such as sonication, SeraCare has developed a breakthrough technology that produces the most patient-like materials compared to native ctDNA. The Seraseq ctDNA Mutation Mix v2 is a highly multiplexed product for NGS-based ctDNA assays targeting cancer-relevant somatic mutations.

This specific ctDNA Reference Material v2 product has an allele frequency of 0.125%.

• Size distribution, library yield and complexity consistent with native ctDNA
• Single sample with 40 clinically-relevant mutations across 28 genes, all at the same specified allele frequency
• Offered in a full-process plasma-like material capable of assessing the entire workflow from extraction through analysis
• Mutation targets precisely quantitated with digital PCR
• Single well-characterized GM24385 human genomic DNA as background wild-type material
• Manufactured in GMP-compliant and ISO 13485-certified facilities

Find more data and in-depth technical information by reading this technical product report.

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