Seraseq® Tumor Mutation DNA Mix v2 AF 10 HC

The Seraseq Tumor Mutation DNA Mix v2 (AF10) HC is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices to an allelic frequency of 10%, and is offered in a high concentration (HC) format at 25 ng/µL. Designed to assess the overall performance of your somatic mutation assay by next-generation sequencing (NGS), this unique product includes a wide range of single nucleotide variants (SNVs), insertion-deletion mutations (indels), and structural variants (SVs).

• Single-vial format for daily run use
• 40 unique multiplexed variants across 28 genes (see table in Specifications tab)
• 20 SNVs
• 5 SNVs that are part of homopolymers
• 13 indels
• 2 SVs
• Mutation targets quantitated with digital PCR
• Well-characterized GM24385 human genomic DNA as background wild-type material
• Manufactured within cGMP-compliant, ISO 13485-certified facilities

The Seraseq Tumor Mutation Mix-II DNA Mix v2 (AF10) HC is formulated for use with targeted next-generation sequencing (NGS) assays that detect mutations in key oncogenes and tumor suppressor genes. The Seraseq Tumor Mutation Mix-II DNA Mix v2 (AF10) HC is intended as a quality reference material for translational and disease research testing to monitor library preparation, sequencing, and variant allele detection under a given set of bioinformatics pipeline parameters.

For research use only. Not for use in diagnostic procedures.

Solid Tumor FAQs

Review the common questions we receive from our customers and the responses we provide.

LEARN MORE