Seraseq™ Lung & Brain CNV Mix, + 6 copies

Copy number variations (CNV) are genomic changes that lead to higher (amplification) or lower (loss) gene copies in comparison to a reference genome. Cells that are affected by aberrant copy number changes for certain cancer-associated genes may experience disruption of normal cellular function and, ultimately, tumorigenesis. Next-generation sequencing (NGS) can be used to determine CNVs across multiple genes in a sequencing run. However, without a widely adopted standard for CNV profiling, NGS assays may evaluate dosage for different targets using different wet and dry methods. In response, SeraCare has developed the first disease-specific CNV reference materials to support clinical labs performing NGS-based tumor profiling of lung and brain cancer patient samples.

• Single sample with three clinically-relevant CNVs (save acquisition and sequencing costs)
• Develop, optimize, and validate your assay’s ability to detect a range of copy numbers (amplifications)
• CNV targets precisely quantitated with digital PCR
• Single well-characterized GM24385 human genomic DNA as background wild-type material
• Manufactured in GMP-compliant, ISO 13485-certified facilities

This specific CNV Mix for lung and brain cancer includes 6 copies.

Also Available:
Seraseq™ Lung & Brain CNV Mix, + 3 copies
Seraseq™ Lung & Brain CNV Mix, + 12 copies

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