IVD Assay Development

Seraseq® FFPE Solid Tumor CNV Reference Materials

Material Number 0710-2865
Size 1 x 10 µm
Inventory Status In Stock
Unit EA

Gene amplifications and deletions, collectively called copy number variations (CNVs), are common in cancer cells and contribute to uncontrolled cell growth, drug sensitivity and resistance. To support clinical labs performing NGS-based tumor profiling of cancer patient samples and help assay developers develop and characterize the performance of their assays, LGCSeraCare has developed a comprehensive solid tumor CNV reference material in formalin-fixed paraffin-embedded (FFPE) format.

FEATURES AND BENEFITS

  • 12 clinically relevant CNVs associated with solid tumors
  • A single reference material carrying gene amplifications at various levels
  • Copy numbers quantified using sensitive dPCR assays and blended with the well-characterized GM24385 genomic background
  • Validated by a targeted NGS panel• Manufactured in GMP-compliant, ISO 13485-certified facilities

Seraseq FFPE Solid Tumor CNV RM Package Insert

Doc type
Package Insert

Seraseq® FFPE Solid Tumor CNV Reference Materials

Doc type
Product Sheet

Seraseq FFPE Solid Tumor CNV RM Technical Product Report

Doc type
Certificate of Analysis/Technical Product Report
Lot #
10659111

Seraseq FFPE Solid Tumor CNV RM Product Sheet

Doc type
Product Sheet

Seraseq FFPE Safety Data Sheet

Doc type
Safety Data Sheet

Seraseq FFPE Solid Tumor CNV Reference Materials

Doc type
Certificate of Analysis/Technical Product Report
Lot #
10690773

Technical Spreadsheet for Seraseq FFPE Solid Tumor CNV Reference Material and Seraseq Solid Tumor CNV Mixes

Doc type
Technical Spreadsheet
# of CNVs 12 (AKT2, BRAF, EGFR, ERBB2, FGFR3, KIT, KRAS, MET, MYC, MYCN, NTRK1, PIK3CA)
Copy Numbers >3 copies of each gene
Format FFPE
Size 1 x 10 µm curl/vial
DNA Yield* >100 ng

*From 1x10 µm FFPE curl using Autogen XTRACT16+ Genomic DNA One-Step Kit/Qubit dsDNA HS Assay

Solid Tumor FAQs

Review the common questions we receive from our customers and the responses we provide.

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