Reproductive Health
Seraseq® 22q11 Male Twins Matched cfDNA
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The Seraseq 22q11 Male Twins - Matched cfDNA is intended as a reference material for non-invasive prenatal testing (NIPT) (or cell-free DNA (cfDNA) analysis) of fetal microdeletions in twin pregnancies.
This product is derived from a naturally occurring mixture of matched (or related) maternal and fetal circulating cell-free DNA, obtained from the blood sample of a twin pregnancy donor whose male twin fetuses have been diagnosed with a 22q11 microdeletion, also known as DiGeorge syndrome.
Supplied as purified cfDNA in 0.1X TE buffer, the Seraseq Euploid Male Twins - Matched cfDNA can be used as a reference material in assay development, validation, verification, analysis and routine monitoring of test performance as well as troubleshooting and training.
- Clinically sourced: derived from naturally occurring cfDNA from a twin gestation, accurately reflecting the challenges and complexities of these cases.
- The only reference material compatible with a broad range of NIPT methods, including SNP-based NIPT assays.
- Proprietary method preserves native cfDNA characteristics such as size profile of ~170 bp, SNP content and natural maternal-fetal size difference. This ensures the material behaves like patient samples.
- High-quality Quality Assured 3rd party control: lot-to-lot consistency with materials manufactured in GMP-compliant and ISO 13485-certified facilities under strict quality controls.
- Easy to use & highly stable: supplied as purified cfDNA in 0.1X TE buffer with 4 years long shelf-life and which can be added during the library preparation step