Accukit™ Myeloid DNA IS Fragmented

Standardized Nucleic Acid Quantification for Sequencing (SNAQ^™-SEQ) is a critical QC method to provide variant specific sensitivity controls for therapeutically relevant Acute Myeloid Leukemia (AML) targets in each sample. Mixtures of synthetic DNA created to mimic the sample regions of interest are added to each sample prior to NGS library preparation; they covary through the complex chemistry, flow cell detection and bioinformatics workflow, mirroring the samples native target template to provide the ideal assay run control. Internal standards (IS) bring the reference material directly into the sample, eliminating the need for external run controls for more cost-efficient reagent and flow cell utilization, while also providing direct QC of the sample.

Accukit^™ Myeloid DNA IS (fragmented) are added to each sample as a single reagent addition, represent genomic regions with clinically relevant cancer driver variants, and are compatible with hybrid capture and amplicon-based library prep chemistries. This Accukit is pre-fragmented to be compatible with cfDNA optimized assays.

LGC is proud to be the exclusive distributor for North America, UK and Europe.